Confirmation of the Effectiveness of the Diabetes Prevention Program

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) conducted a study to determine if weight loss could prevent type 2 diabetes. The study was called the Diabetes Prevention Program (DPP). The researchers concluded that a relatively small amount of weight loss resulting from diet, exercise and lifestyle modifications can be more effective in preventing type 2 diabetes for those people with prediabetes than metformin. And a recent study confirms that actions an individual can take that include lifestyle modifications can be more effective in treating prediabetes than metformin.

The Diabetes Prevention Program or DPP trial was initiated in 1996 by the NIDDK to determine if weight loss could be used to prevent type 2 diabetes in persons with prediabetes. The study was a randomized trial consisting of three groups. All three groups contained prediabetic subjects that were overweight but not obese. Results from the trials were reported in 2002.

Subjects in one of the groups received placebo treatment for type 2 diabetes treatment. Subjects in another group were given the diabetes drug metformin. And subjects in the third group were provided intensive lifestyle intervention, with the goal of a 7% weight loss using diet, exercise and lifestyle modification.

The specific goal of the study was to determine if individuals with prediabetes could avoid type 2 diabetes by losing 7% of their weight through diet, exercise, and lifestyle modification. Actually, all three groups lost weight. At one year, the intensive lifestyle group lost 7.1% of their weight, compared to 1.5% for the metformin group and 1% for the placebo group.

Participants spent an average of 2.8 years in the study. And during that time, it was found that the intensive lifestyle subjects experienced a 58% reduction in the incidence of type 2 diabetes, and the metformin group experienced a 31% reduction compared to the placebo group. And after ten years, the type 2 incidence "was reduced by 34% ... in the lifestyle group and 18% .. in the metformin group compared with placebo."

And researchers from the more recent study mentioned above indicated that "the combination of dietary methods and physical activity in lifestyle modification intervention is more effective in reducing the risk of diabetes..."

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Below is a quillbot version of the above post.

A study was carried out by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to see if losing weight helped fend off type 2 diabetes. The Diabetes Prevention Program (DPP) was the name of the study. The researchers came to the conclusion that for those with prediabetes, weight loss resulting from lifestyle modifications, including diet and exercise, can be more effective than metformin at avoiding type 2 diabetes. And a recent study confirms the idea that lifestyle changes and other preventative measures can be more successful at treating prediabetes than metformin.

The NIDDK started the Diabetes Prevention Program or DPP trial in 1996 to see if people with prediabetes may avoid type 2 diabetes by losing weight. Three groups were included in the investigation, which was a randomized trial.

One of the groups' participants received a placebo as treatment for type 2 diabetes. Another group of participants received the diabetes medication metformin. The third-group's participants received extensive lifestyle interventions with the aim of losing 7% of their body weight using food, exercise, and lifestyle change.

The study's specific objective was to determine if people with prediabetes might avoid developing type 2 diabetes by decreasing 7% of their body weight through diet, exercise, and lifestyle changes. In reality, weight was lost by all three groups. At one year, those who followed an intensive lifestyle dropped 7.1% of their body weight, compared to 1.5% for those who took metformin and 1% for those who received a placebo.

An average of 2.8 years were spent by participants in the study. And it was discovered that over that time, the incidence of type 2 diabetes decreased by 58% in the intensive lifestyle group and by 31% in the metformin group compared to the placebo group. The incidence of type 2 diabetes also "decreased by 34%... in the lifestyle group and 18%.. in the metformin group compared with placebo" after ten years.

Researchers from the more current study, mentioned above, also concluded that "the combination of dietary methods and physical activity in lifestyle modification intervention is more effective in reducing the risk of diabetes..." than metformin or placebo.

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