Intensive Lifestyle Intervention Can Benefit Health While Changing Our Microbiota
Trillions of
microbiota live
in our gut. Some of these microbiota
perform activities such as the extraction of
calories from food and the management of
nutrients. While the microbiota are common to
all people, each individual has a unique set of
the microbiota. And some of the microbiota have
a positive impact on our health, while some do
not. And one study
has concluded that intensive lifestyle
intervention plus an energy-restricted
Mediterranean diet can improve heath while
causing a change in certain microbiota.
The study consisted of two groups: an intensive
lifestyle intervention group (IG) and a control
group (CG). Both groups followed a Mediterranean
diet. The IG participants followed an
energy-restricted Mediterranean diet and the
participants were advised to engage in physical
activity. The CG participants followed a non
energy-restricted Mediterranean diet with no
advice on physical activity.
The study consisted of men and women from the
age of 55 to 75. Participants did not have a “documented
history of cardiovascular disease at baseline.”
The participants' BMI ranged from 27 to 40. Each
participant also had at least three of the
components of metabolic syndrome as defined by
the American Heart Association and the National
Heart, Lung, and Blood Institute.
There were 400 participants in the study. The
participants were randomized to one of the two
groups, each group consisting of 200 subjects.
The CG participants received information on the
Mediterranean diet, along with one individual
and one group session every six months, to keep
the participants on track. The information was
delivered by trained dietitians and nurses.
The IC participants received more individualized
attention, including motivational interviewing
delivered by trained dietitians. The IC group
also participated in group sessions. And for one
year, the IC participants received a monthly
follow-up phone call. The IC group members were
also given specific weight loss goals.
At the end of the one-year study, the
researchers concluded that for the IC
participants, there was a decrease in
“BMI, fasting glucose, glycated hemoglobin, and
triglycerides and an increase in HDL
cholesterol” compared to the CG participants.
There was also a decrease in microbiota,
including "Butyricicoccus, Haemophilus,
Ruminiclostridium 5, and Eubacterium hallii in
the IG compared with the CG."
So, there seems to be a relationship between
an intensive lifestyle intervention, plus a
Mediterranean diet, and gut microbiota. Of
course, more research is needed to determine
what the relationship is, but the combination of intensive
lifestyle intervention plus a healthy diet, once more, appears to be a
key tool for improving health.
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