Thursday, March 19, 2020

A Low-Carbohydrate Diet in Conjunction with Alternate Day Fasting May be Feasible

Intermittent fasting, an eating pattern technique where an individual follows a zero calorie or very low-calorie diet on some days of the week, and follows a regular eating pattern on the other days, is a recognized method for weight loss and glycemic improvement. Low carbohydrate diets are also recognized as a way to lose weight and improve glycemic control. And one study has combined intermittent fasting, in the form of alternate day fasting, with low carbohydrate diets to improve weight and other metabolic processes.

The study combined ADF with a low carbohydrate diet. Ninety-four subjects with obesity (BMIs pf 30 to 49.9) in the Chicago area were selected for the study. Thirty-one subjects completed the study. For the ADF design of the diet, participants ate 600 calories during the fasting days, consisting of 30% carbohydrates, 35% protean, and 35% fat. For the low-calorie design of the diet, participants chose their food ad libitum during the “feast” days, to form a diet, again, consisting of 30% carbohydrates, 35% protean, and 35% fat.

The weight loss study lasted six months, with the first three months being a weight loss period. And the last three months being a weight maintenance period. Meal replacements were used to enable the study participants to take in the desired macronutrient content during the six month study period, while adhering to the 600 calorie limit during the fast days.

At the six month period average weight loss was 6.3%, total cholesterol was reduced by 6% and the LDL was decreased by 8%. There was a decrease in systolic blood pressure by 7 mmHg, and there was a decrease in fasting insulin of 8%.

The investigators concluded that while more research is required, the “findings suggest that ADF combined with the low carbohydrate diet is effective for weight loss, weight maintenance, and improving certain metabolic disease risk factors such as LDL-cholesterol, blood pressure, and fasting insulin.” The study shows that ADF plus low carbohydrate diet is an eating pattern that probably should be given some consideration by healthcare providers.


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