Belviq May Give Weight Loss Drugs a Boost
In general, there are three approaches to weight loss and
weight management. These approaches are lifestyle
modification (including diet and exercise), weight
loss surgery, and antiobesity drugs. While each
approach can be successful, each one of these
approaches has associated problems. Changes in
lifestyle are hard for individuals to adhere to for
a long period of time. Weight loss surgery can give
rise to serious complications. And antiobesity drugs
have often produced disappointing weight loss
results and severe side effects. But one drug,
Belviq, is showing positive results.
Over the past several years, four antiobesity drugs have gained FDA approval and become available for the treatment of obesity. These drugs are Qsymia (phentermine/topiramate), produced by Vivus, Belviq (lorcaserin) produced by Arena, Contrave (bupropion/naltrexone), produced by Orexigen and Saxenda (liraglutide), produced by Novo Nordisk. These drugs give providers new tools to fight obesity. But the drugs have not had the impact that some desired.
However, one of the antiobesity drugs, Belviq, may change that. For example, according to one study, Belviq did not increase the participants' risk of major cardiovascular events compared to the placebo group. Cardiovascular problems have been a concern since the days of the antiobesity drug, fen/phen (fenfluramine/phentermine), which was taken off the market in 1997.
Also, "Weight loss of at least 5% occurred in 38.7% of those assigned [Belviq] vs. 17.4% of those assigned placebo." Further, the "Researchers observed small but significant improvements in in BP, heart rate, triglyceride levels and HbA1c during the course of the study ..."
Over the past several years, four antiobesity drugs have gained FDA approval and become available for the treatment of obesity. These drugs are Qsymia (phentermine/topiramate), produced by Vivus, Belviq (lorcaserin) produced by Arena, Contrave (bupropion/naltrexone), produced by Orexigen and Saxenda (liraglutide), produced by Novo Nordisk. These drugs give providers new tools to fight obesity. But the drugs have not had the impact that some desired.
However, one of the antiobesity drugs, Belviq, may change that. For example, according to one study, Belviq did not increase the participants' risk of major cardiovascular events compared to the placebo group. Cardiovascular problems have been a concern since the days of the antiobesity drug, fen/phen (fenfluramine/phentermine), which was taken off the market in 1997.
Also, "Weight loss of at least 5% occurred in 38.7% of those assigned [Belviq] vs. 17.4% of those assigned placebo." Further, the "Researchers observed small but significant improvements in in BP, heart rate, triglyceride levels and HbA1c during the course of the study ..."
Therefore, the study may motivate providers to
prescribe Belviq for weight loss. One stumbling
block is the cost of the drug, which is $280.00
per month, retail. But if the cost-benefit
ratio can be justified by payers, and if commercial
insurers start to reimburse providers for the drug,
the drug will likely see an increase in use.
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