Monday, August 14, 2017

Determining the Best Diet for a Person with Prediabetes or Type 2 Diabetes



It is becoming more and more apparent that no single weight loss or weight maintenance approach will work for everybody. For example, no type of exercise that works for one person will necessarily work for another. An anti-obesity drug that causes one person to lose weight might not cause someone else to lose weight. And a diet that enables one individual to lose weight may actually cause someone else to gain weight. So biomarkers that indicate what might work for a specific person would be valuable for designing personalized weight loss and weight maintenance approaches. And these types of biomarkers are being looked at. With respect to diet, fasting plasma glucose and insulin may be biomarkers that can aid in diet personalization.

A study was done at the University of Copenhagen to determine if fasting plasma glucose and fasting insulin could be used to predict the diets that would lead to weight loss for specific people. The researchers looked at 1200 subjects in three clinical trials. And the researchers concluded that “for most people with prediabetes, a diet rich with vegetables fruits and whole grains should be recommended for weight loss and could potentially improve diabetes markers. For people with type 2 diabetes, the analysis found that a diet rich in healthy fats from plant sources would be effective for achieving weight loss. These diets could also be effective independent of caloric restriction.”

As always, more research is needed, and the researchers at the University of Copenhagen will continue to investigate fasting plasma glucose and insulin. And if further research indicates that these two biomarkers, and other biomarkers, can indeed provide insight into which diets would be the most beneficial for specific individuals, the research could provide important weapons for the fight against weight loss and diabetes.

These kinds of predictive mechanisms should be embraced by primary care physicians and other providers engaged in providing obesity medicine. Indeed, these types of biomarkers should be of particular interest to obesity medicine specialists.

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