Wednesday, January 26, 2022

Prediabetes Raises the Risk of All-Cause Mortality, and Diabetes-Related Conditions

The CDC estimates that 96 million American adults have prediabetes. And most persons with prediabetes don't know that they have the condition. The CDC’s Diabetes Prevention Program study that took place between 1996 and 2002 showed that lifestyle intervention can reduce the risk of progression from prediabetes to diabetes by 58% compared to people with prediabetes who were receiving usual care. And a recent study suggests that prediabetes raises the risk of all-cause mortality, comorbidities and complications.

The study was carried out by analyzing the results from different meta-analyses to determine how prediabetes is related to new cases of complications typically associated with diabetes. The researchers studied 4807 articles containing prediabetes-related meta-analyses. And the researchers narrowed the number of articles that fit the selection criteria to 16 articles, from which 95 meta-analyses were chosen.

The researchers concluded that “Prediabetes was associated with a higher relative risk of all-cause mortality and higher incidences of CV [cardiovascular] events, CHD [coronary heart disease], stroke, heart failure, atrial fibrillation, chronic kidney disease, total cancer, liver cancer, hepatocellular carcinoma, breast cancer and all-cause dementia with moderate certainty of evidence."

The researchers indicated that the incidence of the comorbidities and complications was lower for prediabetes than type 2 diabetes "suggesting a dose–response gradient in the relationship with complications."

The meta-analyses study highlights the importance of addressing prediabetes. We know that prediabetes raises the risk of diabetes. But the study shows that prediabetes raises the risk of other diseases. Therefore, healthcare providers should counsel at-risk prediabetes patients. They should work with the patients, if appropriate, to get the patients into a diabetes prevention program.

These programs can delay or prevent diabetes which could increase the lifespan of a person with prediabetes. Delaying or preventing diabetes can not only increase a person’s lifespan, it can also lower the person’s healthcare costs.


Tags: , , , , , ,


Post a Comment

Subscribe to Post Comments [Atom]

<< Home

Subscribe to Overfat Strategy Blog by Email